[5] It is on the Left Rhine line (German: Linke Rheinstrecke) and is the terminus of the Cross Eifel Railway (Eifelquerbahn).

Andernach received a rail extension of the Rhenish Railway Company’s Left Rhine line from Oberwinter to Weißenthurm on 15 August 1858.

[10] The only facility available at the station is a Deutsche Bahn (DB) ticket office, which has two counters.

Long-distance services stopping at the station consist of Intercity-Express and Intercity trains.

Regional services consist of Regional-Express (RE) and Regionalbahn (RB) trains to cities within 200 kilometres, running towards Cologne/Emmerich, Koblenz, Mainz and Mayen/Kaisersesch.