[3] He, along with fellow Workaholics creators Blake Anderson, Adam DeVine, and Kyle Newacheck, formed the sketch group Mail Order Comedy.

Holm made a guest appearance with fellow Workaholics actors Anderson, DeVine and Erik Griffin on the first episode of the fourth season of Arrested Development.

He has served as production and head writer's assistant for Real Time with Bill Maher before his work on Workaholics.

Holm has appeared in films involving Seth Rogen, such as Neighbors, The Interview (both 2014), and Sausage Party (2016).

[11] Also that year, Holm co-produced The Package, a Netflix original film comedy that premiered on August 10.