Andrea and her four siblings Antonio Irineo, Teresa, Próspero and Alfonso were exposed early on to the social issues in their town.

[2] Andrea gave her vocal support to the anarchist and communist Partido Liberal Mexicano (PLM) opposing the dictatorship of President Porfirio Díaz (1876–1911), during the Mexican Revolution of 1910–1917.

Andrea along with other women such as Blanca Moncaleano, Teresa Arteaga, and Maria Talavera played key roles in the revolution when leaders of the PLM were arrested.

Advertised through the Regeneracion, Andrea composed postcards about the revolution including portraits of revolutionaries that confronted the Diaz tyranny.

The Villarreals use bold statements about bravery, cowardliness, and rightful duty to challenge the Mexican men who choose to act as bystanders.

Andrea praises their heroics and bravery, and claims that it is better to give your life in war than prolong the state of slavery they suffer under Diaz.