Standing at 2.05 metres (6 feet 9 inches), he plays at the forward-center positions.

At 21 years old he signed a contract with Ruvo di Puglia Basket where he got 9 points per match, with 55% from 2 and 31% from 3 shots.

[3] The 2011-12 LBA season was Zerini's first time in the top-tier of the Italian basketball league system.

On 20 June 2016 Andrea Zerini signed a contract with the LBA club Sidigas Avellino.

[6] On 28 July 2020 Zerini signed with Napoli Basket in the Italian second league Serie A2.