Andrea de Litio (active 1442–1473) was an Italian painter.
His city of birth is uncertain; one possibility is Lecce nei Marsi in the Province of L'Aquila in the Abruzzo.
His masterworks are frescoes in the choir of the canons in Atri Cathedral.
These include a depiction of the evangelist Saint Luke as a painter.
Other frescoes have primitive oddities: such as his depiction of The Massacre of the Innocents.