[1][2] Andreas was born to Lars Eriksson (1605-1674) and Karin Matsdotter (1610-1682) in midst of the 30 Years' War (1618–1648).
[3] With his career choice Andreas detached himself as well as all his future offspring from the family's long time tradition of farming and operating a plantation, which his father Lars, grandfather Erik and great-grandfather Bengt had represented in Uppland, Sweden.
[4][5] Andreas Hackzelius became the first rector – head of a congregation – to oversee the newly constructed Church of Holm, erected in 1678 in the Parish of Holm, between Lårstaviken and Gorran in Mälaren, 17 km north of Bålsta, in the municipality of Enköping in Uppland, Sweden.
[6] In the 17th century, the patronage of the Church of Holm consisted of high-ranking statesmen, clergymen, military officers as well as royal and other high noble friends and family members of Stenbock.
In a 17th-century letter remaining, the Queen of Sweden Christina (1626–1689) compliments and thanks Rector Andreas Hackzelius for a church service and sermon given by him.