He was a member of the Maryland Senate from District 2, which covers parts of Washington County, from February 2015 to August 2020.

After high school, he went to Shippensburg University in south central Pennsylvania where he received a degree in Business Administration in 1983.

He was the chair of the Board of Trustees for Grace Academy (where he coached the boys' varsity soccer team to a national title), in Hagerstown from 2005 until 2007 and has been the vice-chair since 2008.

On February 2, 2015, Serafini was sworn into the Maryland State Senate to replace Christopher Shank who resigned to become director of the Governor's Office of Crime Control and Prevention.

[4] Serafini cited long hours and stress, the demands of his financial adviser job, and wanting to spend more time with his family.