Andrew James Santino (born October 16, 1983) is an American stand-up comedian and actor.

He is known for television series and films such as Sin City Saints, The Disaster Artist, Mixology, I'm Dying Up Here, Beef, and Dave.

Santino graduated from Naperville North High School in 2002, and then attended Arizona State University.

[7] On I'm Dying Up Here, Santino played Bill Hobbs, a talented, popular comedian who sabotages himself with a bitter attitude and negative outlook on life.

[8] He stars in the series Dave, which tells the fictionalized story of rapper Lil Dicky; Santino portrays his roommate and manager.