[1][3] In 2045, Los Angeles Police Department detective Hammond (Michael Jai White) and his new partner "Andy" (Randy Wayne) — a state of the art crimefighting robot cop — are tasked with recovering a runaway Telepresence android containing the consciousness of Mayor Jacobs's (Charles S. Dutton) daughter Helen (Larissa Vereza), who remains unaware that she is a human mind in a machine body.

Hammond does not trust machines due to a prior incident in which his partner was killed by an automated gun turret despite their using a code to control it, and maintains a tense, often sarcastic relationship with Andy.

However, they are unaware that a number of their fellow LAPD officers are corrupt, working for Mayor Jacobs himself in a plan to provoke violence with the goal of justifying an invasion of the Zone and termination of its residents.

She reveals to them that Zone residents are giving birth to healthy, mutation-free children, causing them to realize that the story about nuclear leaks was a lie.

En route to what they believe to be an extraction point, Hammond, Andy and Helen realize that the lie about nuclear leakage was spread to manipulate land prices, and that the real source of the disease is the food drop program for which Mayor Jacobs has received honor.

As a desperate, last-ditch attempt to salvage their plans, the corrupt cops disconnect Hammond and Helen's life support, leaving them with only around twenty minutes before their android bodies shut down.