As the Program Coordinator of the Market Vendors AIDS Project (MAVAP), she transformed Kampala's markets into a one stop shopping where vendors and customers do trade but are also encouraged to check their HIV status and get treatment.
[3] Wapakhabulo was born and raised in the Iringa District of Tanzania.
While a student at the University of Dar es Salaam,[citation needed] she met James Wapakhabulo (23 March 1945 – 27 March 2004), the late former Minister of Foreign Affairs, from 2001 until 2004.
Their daughter, Josephine Wapakabulo is the former Executive Director of Uganda National Oil Company.
[4] Wapakhabulo and her husband were contemporaries at Dar es Salaam University, with President Yoweri Museveni in the 1960s.