The Angola Horror[note 1] train wreck occurred on December 18, 1867, just after 3 p.m. when the last coach of the Buffalo-bound New York Express of the Lake Shore Railway derailed at a bridge in Angola, New York, United States, slid down into a gorge, and caught fire, killing some 49 people.

As the train neared the truss bridge over Big Sister Creek just east of Angola at 3:11, it ran over a frog (the crossing point of two rails).

[9] The last car plunged 40 feet (12 m) down the ice-covered slope to the gully bottom and came to a rest, at a 45-degree angle, with a fearful crash.

Frank Leslie's Illustrated Newspaper carried five sketches of the scene[11] and concluded, "This railroad disaster is accompanied by more horrible circumstances than ever before known in this country, and its results are truly sickening to contemplate".

[10] The accident and the public outcry that arose from it influenced many railroad reforms that soon followed, including the replacement of loosely secured stoves with safer forms of heating, more effective braking systems and the standardization of track gauges.

[10] In 2008, the villagers of Angola reserved a .03-acre (0.012 ha) parcel of land along Commercial Street[12] and erected a sign to mark the site of the accident, dedicated to its victims.