[2] He is notable for his portrayal of Angry Joe, the titular host of his media review-oriented YouTube channel AngryJoeShow.

[3] Vargas launched his YouTube channel AngryJoeShow on October 4, 2008 with the video "Shit that Pisses Me Off - Madden 2009 Hardcore Gamers".

The channel was well-received by the YouTube community;[5] as of April 2021, it has accrued over one billion views and amassed more than 3.2 million subscribers.

[11][7][12] Vargas was affiliated with Blistered Thumbs of the media production company Channel Awesome until April 2018.

His departure was due to the then-ongoing controversy regarding Channel Awesome and many of its former producers, many of whom Vargas had previously known and affiliated with in the past.