Prior to his current role as CEO of Unity Biotechnology,[2] he held senior positions at several academic institutions and companies.
Ghosh served on the faculty of Johns Hopkins School of Medicine and as Chair of Neurobiology at UCSD, where he made significant contributions in the field of Neuroscience in the areas of molecular mechanisms of synapse formation and activity-dependent development of neural circuits.
[1] While at Johns Hopkins his laboratory cloned CREST as a calcium-regulated transcription factor and showed that it plays a critical role in brain development.
Work from Ghosh and his colleagues at UCSD established the role Leucine-rich Repeat (LRR) proteins in the development and function of synaptic connections.
[4] Ghosh was appointed CEO of UNITY Biotechnology in 2020, a company focused on developing therapies to slow, halt, or reverse diseases of aging.