She played as a striker, midfielder and defender and only switched to the goal at the age of 16, joking she became "lazy to run," and "has grown" again.

[7] She was the starting goalkeeper in three of Potsdam's 2011–12 UEFA Women's Champions League matches helping the squad earn shut-outs against Þór Akureyri and Glasgow City F.C.

[6][8] Berger signed with Paris Saint-Germain in June 2014, playing 22 matches in all competitions during her two-year spell with the club.

On 4 February 2018, she made her first appearance since being diagnosed with cancer in the Fourth Round of the 2017–18 FA Women's Cup in an away match against Reading.

[12] Berger continued her strong return in 2018, helping Birmingham City to a fourth-place standing after midway point of the 2018–19 FA WSL season.

[15] In April 2021, Berger made title winning saves away against Manchester City in a 2–2 draw, as Chelsea fought to preserve their lead at the top of the table.

Chelsea broke the records for most wins (18) and most points (57) in a season, and became just the third team to defend the League title after Liverpool and Arsenal.

[19] In March 2023, Berger made the decisive save on Lindsey Horan's shot in the penalty shootout with Lyon, to take Chelsea to the semi-finals in the Women's Champions league.

[33] Berger is an Ambassador and co-founder of the Judan Ali Football Academy known as JAFA based in London and founded in 2019.