She was the wife of William Henry, a gunsmith, inventor, delegate to the Continental Congress, and patriot in the American Revolution.
According to the best available information, Ann Henry was an upper-class woman with means who was primarily focused on attending to the domestic sphere of her and her husband's household.
[4] William held multiple leadership positions in the state in judicial, legislative, and military spheres.
During the British occupation of Philadelphia, David Rittenhouse, then Treasurer for the Commonwealth of Pennsylvania, stayed in the Henry home, as did Thomas Paine, who wrote his fifth Crisis there.
William Henry continuously fought sickness and eventually died from it which left Ann as his widow.