Panagiotopoulou was born in Kypseli, Athens, Greece on 30 July 1945.
She became famous after starring in the Greek series Madam Sousou in 1986.
In 1995, she starred in another successful series Ντόλτσε Βίτα as Christina Markatou.
[2] Panagiotopoulou also enjoyed a successful film career, having appeared in several commercially and critically successful films such as Safe Sex (1999) and To Klama Vgike Apo ton Paradiso (Crying... Silicon Tears) (2001).
Panagiotopoulou died from complications of Alzheimer's disease in Athens.