Elections were held on November 2, 2010, to determine Mississippi's four members of the United States House of Representatives.

[5] The Republican Party flipped the 1st and 4th districts, defeating incumbent Democrats Travis Childers and Gene Taylor, respectively.

[8] Results of the 2010 United States House of Representatives elections in Mississippi by district:[9] Nunnelee:      40-50%      50-60%      60-70%      70-80% Travis Childers Democratic Alan Nunnelee Republican In 2010 the 1st district included Horn Lake, Olive Branch, Southaven and Tupelo.

[10] In May 2009 Childers denied planning to switch parties and seek re-election as a Republican, describing himself as a "Southern Democrat".

[12] In 2010 the Republican nominee was Alan Nunnelee, a member of the Mississippi State Senate.

[13] A. G. Baddley, an electrician;[14] Les Green, a teacher;[15] Rick "Rico" Hoskins; and Wally Pang, a retired restaurateur,[16] ran as independent candidates.

Gail Giaramita, a nurse, ran as the Constitution Party nominee.

[18] Barbara Dale Washer, a teacher, ran as the Reform Party nominee.

[19] Angela McGlowan, a Fox News political analyst;[20] and Henry Ross, a former mayor of Eupora,[21] also ran for the Republican nomination.

Greg Davis, the mayor of Southaven who ran unsuccessfully in both 2008 elections, said in March 2009 that he would not run again in 2010.

[22] Merle Flowers, a member of the Mississippi Senate, met with the National Republican Congressional Committee in June 2009, but ultimately decided not to run.

[28] Sabato's Crystal Ball rated the race as "Leans Republican".

[36] George Bailey and Richard Cook, a teacher, also ran in the Republican primary.

[31] Marcy ran again in the 2nd district in 2012 and sought the Democratic nomination for the U.S. Senate in 2014.

[48] James D. Jackson, a sociology professor; and Shawn O'Hara, a frequent candidate for office, also sought the Democratic nomination.

[53] Gill unsuccessfully ran for Mississippi Agriculture Commissioner in 2011, and died in a car accident in October 2012.

[58] In 2010 Taylor's opponent in the general election was Steven Palazzo, a member of the Mississippi House of Representatives.

[65] In October 2010 Taylor said his own internal polling showed him leading Palazzo by eight percentage points.

[4] In November 2010 The Rothenberg Political Report rated the race as "Pure Toss-up".