Anna Sologashvili was born into a noble family in the village of Mejvriskhevi near Gori, then part of the Russian-controlled Georgia, in 1882.
After the February Revolution overthrew the Russian monarchy in 1917, Sologashvili became member of the Georgian National Council and voted for the independence of Georgia in May 1918.
She was member of the Women's Committee of the Social Democratic Party of Georgia, which provided aid to political prisoners and their families.
After the futile anti-Soviet revolt in 1924, she was no more politically active and worked as a teacher in the recently created South Ossetian Autonomous Oblast.
At the height of Stalinist Great Purge in 1937, Sologashvili was arrested and hastily tried by the NKVD troika for "anti-Soviet propaganda", "chauvinism", and ties with the emigre politician Noe Ramishvili.