Anna of Saxe-Wittenberg (died: 18 April 1426) was a member of the House of Ascania and the wife of Duke Frederick I of Brunswick-Lüneburg, a German anti-king.
Anna of Saxe-Wittenberg was the daughter of Duke Wenceslas I of Saxe-Wittenberg, Duke of Lüneburg and Elector of Saxony and his wife Cecilia of Carrara.
Frederick was murdered on the way home, a month after the election.
Anna's second marriage was with Landgrave Balthasar of Thuringia, Margrave of Meissen.
From her first marriage to Frederick I, Duke of Brunswick-Lüneburg she had two daughters: