Anne Wetzell Armstrong (September 20, 1872 – March 17, 1958) was an American novelist and businesswoman, active primarily in the first half of the 20th century.

[6] In the late 1920s, Armstrong retired and moved to the Big Creek community in rural Sullivan County, Tennessee, which would provide the inspiration for her 1930 novel, This Day and Time.

[2] Armstrong's first novel, The Seas of God, tells the story of a young woman, Lydia Lambright, and her struggles to survive as an unwed mother amidst the moral constraints of Victorian society.

The story opens in Kingsville, a fictional Southern town (based on Knoxville)[1] where Lydia's dying father, a professor, has been ostracized for teaching the Theory of Evolution.

Unable to find gainful employment, she becomes a prostitute, and while her financial situation drastically improves, she struggles with what she deems a pointless existence.

[8] Armstrong's second novel, This Day and Time, takes place in an early 20th-century rural Appalachian community based primarily on the Big Creek area of Sullivan County, Tennessee.

[2] The story focuses on Ivy, a mountain woman who returns to a life of subsistence farming after spending several distasteful years as a wage-earner in a nearby city.