Annonin

Annonins are a group of chemical compounds classified as acetogenins.

[1][2] Annonin-based bioinsecticides are used to control Coleoptera (beetle) pests commonly found in stored organic cereal and beans in the country of Brazil.

[3] Other different types of annonin-based insecticides, derived from A. mucosa, fight off lepidopteran (moth) pests that infest cabbage leaves, also found in the tropical climates of Brazil.

[4] These annonin molecules act as overpowering inhibitors of complex I (NADH: ubiquinone oxidoreductase) in the electron-transport chain in the mitochondria of quarry pests.

In cell membranes of these same pests, annonins also inhibit coenzyme NADH, causing these arthropods to die.