[2] The disease first manifests in infancy, and if treatment is not received, the periodic eruptions usually stop after the first year of life.

[3] Urticarial papules or slowly growing, raised-bordered annular or circinate erythematous plaques are found upon physical examination.

Individual lesions heal in a few days however, new ones keep coming up until the skin fully clears up, which happens at about a year of age.

[4] Although the exact cause of AEI is unknown, a hypersensitivity reaction to an unidentified antigen is believed to be involved.

[2] Histologic findings include perivascular lymphocyte infiltrates and either neutrophils or eosinophils; they are nonspecific.