While the new station was in its construction permit phase, a temporary working studio and office was set up at 2679 Brookford Drive in Toledo and a tower erected on Sugar Ridge Rd.

It is the second Catholic station to make its debut in the summer of 2010, the other being WJTA "Holy Family Radio" licensed in Glandorf, Ohio and transmitting from Leipsic.

WHRQ (88.1 FM) in Sandusky made its on-air debut on Monday, April 25, 2011, as a WNOC simulcast.

In May 2013 Annunciation Radio opened a permanent main studio and office located at 3662 Rugby Drive in south Toledo.

In July 2013, it purchased Lexington station WFOT (89.5 FM), serving the Mansfield area, from St. Gabriel Radio based in Columbus.