Anton Higueras de Santana (1557–1619) was a Spanish Captain, who served as expeditionary and conquistador.

[1] He was born in Salteras, Sevilla, son of Pedro Correa de Santana and Antonia Morena, belonging to an old Andalusian family.

[4] Santana belonged to the first contingent of founding neighbors of Buenos Aires, who had been arrived with Juan de Garay from Santa Fe.

Towards the year of 1590, he was in charge of a caravan of wagons from the territory of San Miguel de Tucumán and Córdoba to the city of Buenos Aires.

[6] Soon after settling in Buenos Aires, Santana began to hold Council positions in the city, serving as regidor in 1589,[7] and lieutenant governor for 1595.