Lepore's work has investigated the frictions created by the containment and cultural representation of nature.
Beginning in 2007, Lepore photographed in the visitor centers of National Parks, creating images of displays that challenge the expectations of landscape photography.
Describing his images made in these visitor centers, Sarah Lehrer-Graiwer wrote in Artforum that "Lepore homes in on places of rupture that break and undermine photographic illusion.
"Lepore's installation casts the viewer deep into a surreal and uncanny scene by contrasting sculptural anthropomorphism with the odd precision of photographic representation.
"[2] Regarding Lepore's still lives, Joanna Szupinska-Myers wrote that "by echoing the effects of digital editing—constructing what he refers to as an “analog illusion”—Lepore's photograph speaks in a language that it simultaneously subverts.