The mission of the organization is to help raise money for cancer research and provide support for children and their families financially.
[1] The Anthony Rizzo Family Foundation held its fourth annual Cook-Off for Cancer at the Morgan Manufacturing in Chicago, Illinois, on June 2, 2016.
[6][7] The Anthony Rizzo Family Foundation held its sixth annual "Walk-Off for Cancer 5k", at Pine Trails Park in Parkland, Florida.
Participants running the event pay a standard rate of $44.00, which includes a Walk-Off for Cancer T-shirt, Cubs hat, a Nike drawstring back, as well as other various items.
The event raised $960,000, all of which that will go to the Joe DiMaggio Children's Hospital and the University of Miami Sylvester Comprehensive Cancer Center.
[13] Majority of the money raised from the foundation supports the Sylvester Comprehensive Cancer Center at the University of Miami, Florida,[13] Ann & Robert H. Lurie Children's Hospital of Chicago, Illinois,[14] Joe DiMaggio's Children's Hospital, Florida, and The Family Reach Foundation, Illinois.
In 2017, the Anthony Rizzo Family Foundation made $3.5 million in donations to the Ann & Robert H. Lurie Children's Hospital of Chicago.
The foundation contributed to the community by donating autographed items from teammates and other MLB players along with raising awareness on social media.