Antiene (also spelled Antienne[5]) is a rural locality of the Muswellbrook Shire local government area in the Hunter Region of New South Wales, Australia.

[1][2][6] Named after County Antrim in Northern Ireland, the locality was registered as "Antiene" because the request was made in illegible handwriting.

[2][dubious – discuss] The Main North railway line passes through the locality and is the site of a coal unloader, used to unload coal destined for the Bayswater and Liddell power stations.

A railway station opened at the site in 1890 and closed in 1975, no trace of this remains today.

[8] Antiene Post Office opened on 1 October 1906 and closed in 1965.