[5] Historically the stibnite form was used as a grey pigment in paintings produced in the 16th century.

[7] Antimony trisulfide was also used as the image sensitive photoconductor in vidicon camera tubes.

[8] Sb2S3 can be prepared from the elements at temperature 500–900 °C:[5] Sb2S3 is precipitated when H2S is passed through an acidified solution of Sb(III).

[9] This reaction has been used as a gravimetric method for determining antimony, bubbling H2S through a solution of Sb(III) compound in hot HCl deposits an orange form of Sb2S3 which turns black under the reaction conditions.

[11] In the extraction of antimony from antimony ores the alkaline sulfide process is employed where Sb2S3 reacts to form thioantimonate(III) salts (also called thioantimonite):[12] A number of salts containing different thioantimonate(III) ions can be prepared from Sb2S3.