Antioch is an unincorporated community in Delta County, in the U.S. state of Texas.

[1] According to the Handbook of Texas,[citation needed] the community had a population of 25 in 2000.

Originally included in the Moses Williams land grant, the location was settled by 1849 when the Antioch Cemetery's four trustees were granted land title.

Maps from 1936 did not identify the location, although they did indicate a single company and a number of residences.

[2] Antioch is located at the intersection of Farm to Market Road 64 and Farm to Market Road 1528, 6 mi (9.7 km) west of Cooper in western Delta County.