Antiochus of Sulcis (died c. 127 AD) was an early Christian martyr of Sardinia.

He had converted many people in Cappadocia and Galatia to the Christian religion, and was therefore tortured and sent into exile by the authorities.

Antiochus was condemned to work the mines on the island that now bears his name.

The island, inhospitable and isolated during this period, was named Plumbaria at the time, after its source of lead (plumbum).

Antiochus, however, converted his jailer Cyriacus in Sardinia, and had built a small underground oratory on Plumbaria, and was thus condemned to death there.