Antonio Bettini (13 June 1396 – 22 October 1487) was an Italian clergyman, diplomat and writer.
He joined the convent of San Girolamo in Siena in 1439 and worked closely with Pope Pius II.
For Pope Sixtus IV, Bettini may have travelled to France (1474) and Germany (1481).
Bettini was revered by later biographers and sometimes referred to as "Beato" (Blessed) (a step toward canonization), but this designation was never church-sanctioned.
His Monte Santo di Dio (1477) described how one could use science and virtue to reach closer to God.