Antonio Macedaz Serapio (June 13, 1937 – February 19, 2007) was a lawmaker from Valenzuela, Philippines.

He represented Valenzuela's lone district from 1987 to 1998 and the second district from 2004 until his death in 2007.

He died due to heart attack, following a vehicular accident in Nueva Ecija.

[clarification needed][1][2] Antonio M. Serapio Elementary School in barangay Ugong was named after him.

This article about a Filipino politician is a stub.