Antonio de Jesus Villegas (January 9, 1928 – November 16, 1984) was a Filipino politician who served as the 16th Mayor of Manila from 1962 to 1971.

All of the LP senatorial candidates except for Benigno "Ninoy" Aquino were defeated by the opposing Nacionalista Party.

He formed the Libre'ng Pilipino Party (LPP) to run for reelection as mayor in the 1971 local election, and selected journalist J.V.

[4] After losing in the 1971 local mayoral elections to then Manila Congressman Ramon Bagatsing, Villegas and his entire family emigrated to the United States.

Villegas's body was finally buried in a plot located along the rotunda of Manila North Cemetery.