[4][5] Mikos completed undergraduate study in engineering at the Aristotle University of Thessaloniki (Dipl.

[6][5] After his doctoral studies, he performed his postdoctoral work at Massachusetts Institute of Technology and the Harvard Medical School.

[6][4][5] Mikos is the Louis Calder Professor of Bioengineering and Chemical and Biomolecular Engineering at Rice University in Houston, Texas.

[15] In 2021, he began studying 3D printing for tissue engineering and hydrogel systems for bone and cartilage regeneration.

[16][17][18] He co-authored a textbook entitled Biomaterials: The Intersection of Biology and Materials Science.