The old station opened on 10 July 1878 (goods) on the Lines 52 (1894) and 25A (1907).

The old station building was demolished in 1965 and replaced with a stop in 1970 on the new through railway under the Scheldt river on the line 59.

In 2006, the Butterfly Palace, designed by the Richard Rogers Partnership, was built on the location of the old station.

The following services currently the serve the station: Tram lines 4 and 10 serve the station, tram line 1 terminates at the nearby Zuid transport hub.

Bus services 13, 14, 180, 181, 182, 183, 290, 295, 298 and 500 serve the station, these are operated by De Lijn.