In later years, Kher was nominated for Filmfare Best Supporting Actor Award for Dil (1990), Saudagar (1991), Lamhe (1991), Hum Aapke Hain Koun (1994), Chaahat (1996), Special 26 (2013) and Uunchai (2022).

[13] Anupam Kher was born on 7 March 1955 in Simla, in the Patiala and East Punjab States Union of India (now in Himachal Pradesh) into a Kashmiri Pandit family.

[20] He taught drama in Raj Bisaria's Bharatendu Natya Akademi in Lucknow for a small part in his directorial debut movie Sheeshay ka Ghar.

[23] It didn't performed well commercially, but was a huge critical success and was chosen as India's official entry for the Academy Award for Best Foreign Language Film.

[26] The following year, however, none of his films performed well critically or commercially with Rahul Rawail's action drama Arjun co-starring Sunny Deol and Dimple Kapadia being the exception.

[27] This changed in 1986 when he co-starred alongside Amitabh Bachchan in K. Bhagyaraj's crime drama Aakhree Raasta and played the ruthless villain "Dr. Michael Dang" in Subhash Ghai's ensemble actioner Karma, which had Dilip Kumar, Jackie Shroff, Anil Kapoor, Naseeruddin Shah and Sridevi in the lead.

[39][40] The following year, he starred in Indra Kumar's blockbuster romantic comedy Dil, which had Aamir Khan and Madhuri Dixit in the lead roles.

[42] He also collaborated with Yash Chopra for the romantic drama Lamhe, which was a commercial failure, but received positive reception from critics and is now considered a cult classic.

[45] His other box office hits of this period, include Beta (1992), Shola Aur Shabnam (1992), Lootere (1993), Waqt Hamara Hai (1993), Khalnayak (1993), Hum Hain Kamaal Ke (1993), Gumrah (1993) and Darr (1993).

[51] In the late-1990s, he continued to play supporting roles in critically and commercially successful ventures, such as Judwaa (1997), Ziddi (1997), Deewana Mastana (1997), Jab Pyaar Kisise Hota Hai (1998), Kuch Kuch Hota Hai (1998), Bade Miyan Chote Miyan (1998), China Gate (1998), Hum Aapke Dil Mein Rehte Hain (1999) and Haseena Maan Jaayegi (1999).

[52][53] He followed it with four more major successes the same year with Dulhan Hum Le Jayenge, Kya Kehna, Hamara Dil Aapke Paas Hai and Mohabbatein.

[46] In 2001, he had another hit in Jodi No.1 and received praise for his performance in Rehnaa Hai Terre Dil Mein, which didn't do well commercially, but went on to attain cult status in later years.

[63][64][65][66] Remembering his father on his 9th death anniversary, he presented a poem written by Lucknow-based Poet Pankaj Prasun and posted it on social media.

In 2014, Kher has written and starred in a play about his own life called Kucch Bhi Ho Sakta Hai, which was directed by Feroz Abbas Khan.

[20][68] In 2016, Anupam Kher was a narrator in the ABP News documentary TV series Bharatvarsh,[69][70] which showcased the journey from ancient India to the 19th century.

[74] Starting in fall of 2018, Anupam Kher starred in NBC medical drama TV series New Amsterdam[75] as Dr. Vijay Kapoor (a neurologist).