The Vicariate Apostolic of Reyes (Latin: Apostolicus Vicariatus Niuflensis) is a Latin Church missionary ecclesiastical territory apostolic vicariate of the Catholic Church in Bolivia.

Its cathedra is located in the episcopal see of Reyes.

On 1 September 1942 Pope Pius XII established the Vicariate Apostolic of Reyes from the Vicariate Apostolic of El Beni.

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