The Apostolic Vicariate of Savannakhet (Latin: Vicariatus Apostolicus Savannakhetensis) is a territorial jurisdiction of the Catholic Church in Laos.

It is exempt, i.e., not part of any ecclesiastical province and directly dependent on the Holy See and its missionary Dicastery for Evangelization.

The vicariate covers an area of 48,100 km2 in central Laos, including the provinces of Savannakhet, Khammouan and part of Bolikhamxai.

Approximately 12,500 of the 2.7 million people living within the vicariate are members of the Catholic Church.

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