[5] Pengilly has walked for leading designers at Australian Fashion Week, lived and worked in New York, London, Tokyo and Osaka, and fronted major campaigns.

She has worked with top photographers Rankin, Steven Chee, Nick Scott, Nicole Bentley, Pierre Toussaint, James Demitri, Bradley Patrick, and Terry Richardson.

In 2009, Pengilly was named Ambassador for the Melbourne Fashion Festival, working alongside J. Alexander and Doutzen Kroes.

Pengilly began studying acting in her spare time,[2] and attended classes at National Institute of Dramatic Art (NIDA) and Actors Centre Australia.

Viewers thought Pengilly and Yegudkin's elimination was unfair, as fellow contestant Mark Holden had received a lower score and broken rules.

She was ready to move to the United States when she joined the cast of soap opera Neighbours as Chloe Brennan in late 2017.

[16] After leaving Neighbours, Pengilly voiced the role of Amy Haqq in the six-part audio series Gripped: Second Son, which also stars Lincoln Younes and Zoe Carides.

[16] When she appeared on Neighbours, Pengilly split her time between her home in Sydney and Melbourne, where the show's studios are located.