On April 22, 1966 American Flyers Flight 280, flying a Lockheed Electra L-188 on approach to Ardmore crashed into a hill.

This was a flight under charter to the Military Air Command, en route from Monterey, California, to Columbus, Georgia, with a scheduled refueling stop at Ardmore.

Subsequent investigation showed that the pilot was under treatment for arteriosclerosis and diabetes, but that he had falsified information on his application for a First Class Medical Certificate, which would have been denied except for the falsification.

[1] In the year ending July 2, 2009, the airport had 45,729 aircraft operations, average 125 per day: 80% general aviation and 20% military.

Industries at the Airpark including King Aerospace, Higgins Interiors, Inc., Dollar General Distribution Center, East Jordan Iron Works, Carbonyx, Inc., and Online Packaging.