Established artistes such as W.C. Fields, Dan Leno and Marie Lloyd performed during the early years of the theatre's life.
Stars such as Charlie Chaplin, Bud Flanagan & Chesney Allen, Harry Lauder, Stan Laurel, George Formby (Senior) and Eric Morecambe & Ernie Wise performed at the Argyle Theatre at the beginning of their careers.
Previn was told that the booked guest, Yehudi Menuhin, had cancelled because he was "opening at the Argyle Theatre, Birkenhead in Old King Cole".
A large, decorative stone sign that was once attached to the Argyle Theatre's exterior was moved to the Williamson Art Gallery for preservation, prior to demolition.
[3] A department store car park now occupies the site and a play, "Argyle Remembered", was written to commemorate the theatre which is performed by Heswall Musical Society.