The district stretches along the Mexico–United States border and includes the western third of Tucson, parts of Yuma and Nogales, as well as Avondale and Tolleson in Metro Phoenix.

The district was larger than Rhode Island, Delaware, Hawaii, Connecticut and New Jersey combined.

It covers parts of Pima, Yuma, La Paz, and Maricopa counties.

For the 118th and successive Congresses (based on redistricting following the 2020 census), the district contains all or portions of the following counties and communities.

[5] Arizona began sending a seventh member to the House after the 2000 census.