The Arizona Cactus Botanical Garden was a non-profit botanical garden, located at 8 Cactus Lane, Bisbee, Arizona, United States, containing representative samples of over 800 varieties of high desert xerophyte plant life.

[1][2] It was founded by David L. Eppele[3] and has been closed since his death on 19 May 2005.

[4] The Garden featured cactus and succulents from high deserts of the Americas.

All plants were cold-hardy and grown with no supplemental water.

Shade frames and greenhouses contained hundreds of plants under study for hardiness and potential as landscape plants in high Southwestern deserts.