Incumbent Republican governor Jan Brewer was term-limited and could not run for re-election to a second full term in office.

Incumbent Republican secretary of state Ken Bennett was term-limited and ineligible to run for re-election to a third term in office.

Incumbent Republican attorney general Tom Horne ran for re-election to a second term in office.

Incumbent Republican Superintendent of Public Instruction John Huppenthal ran for re-election to a second term in office.

Huppenthal faced down calls for him to resign or withdraw from the race after it was revealed that he made pseudonymous blog posts that attacked welfare recipients, Planned Parenthood and Spanish-language media.