The main segment of 17.31 miles (27.86 km) runs from Devil's Den State Park to West Fork.

[3] A shorter segment of 5.44 miles (8.75 km) runs from U.S. Route 62 (US 62) through Appleby before reconnecting with US 62.

The route runs north, winding through steep Ozark topography.

The route runs over the Cane Hill Road Bridge, and serves Appleby.

The highway was created between 1936 and 1937 as a semicircle loop from Winslow to US 71 near West Fork via Devil's Den State Park.