The route begins at US Highway 425 (US 425) at Terry[a] and runs north 6.79 miles (10.93 km) to US 65 at Linwood.

[3] The area is known for flat, agricultural land with swamps, bayous and small towns dotting the landscape.

The route crosses three bayous and passes through the unincorporated community of Moscow before intersecting US 65, where it terminates.

[4] The route was designated by the Arkansas State Highway Commission on June 23, 1965.

Media related to Arkansas Highway 199 at Wikimedia Commons