Arkansas Highway 352

One section begins at Franklin County Road 441 (CR 441) and runs north 1.11 miles (1.79 km) to US Highway 64 (US 64).

A second segment begins at Highway 23 approximately 5 miles (8.0 km) north of Ozark.

[3] The route begins at Highway 23 north of Ozark in the Arkansas River Valley.

The route is a two-lane rural highway its complete length, paralleling Interstate 40 (I-40) and bridging it twice, though no direct access to I-40 is provided.

It continues east, meeting AR 164 in Hunt before angling south to cross over I-40.