Zakaryan won gold at the Russian National Boxing Championship in November 2012.

[3] On January 31, 2015, he became the AIBA Pro Boxing world champion in his weight category by defeating Artem Harutyunyan, in a closely fought game.

Harutyunyan was declared the winner by split decision of the judges after 12 rounds of boxing.

[5] In 2016 Artem Zakaryan won a gold medal in the Eindhoven Box Cup 2016[6] in the Netherlands.

In the quarterfinals he won against British Royal Navy boxer Luke Fisher (England) by split decision.