[1] Wallace was a music educator in Knoxville public schools,[1][2][3] and a contralto singer,[4][5][6] In 1933 she sang with the Knoxville College octet on a tour, including an appearance at the Diamond Jubilee of the United Presbyterian Church in Pittsburgh.

[9][10] She focused the organization's work on sickle cell research and international expansion during her tenure.

[11] She was chair of the National Pan-Hellenic Council, and was named Knoxville's "Negro Woman of the Year" in 1950.

[12][13][14] She was also the first vice-president of the National Council of Negro Women, and active in the YWCA.

[16] She traveled in Africa and was an honored guest at independence day festivities in Liberia.