Arpino (Southern Latian dialect: Arpinë) is a comune (municipality) in the province of Frosinone, in the Latin Valley, region of Lazio in central Italy, about 100 km SE of Rome.

Connected with the Pelasgi, the Volsci and Samnite people, it was captured by the Romans and granted civitas sine suffragio in 305 BC.

[5] The town produced both Gaius Marius and Marcus Tullius Cicero, who were homines novi (people without ancestors who had held the consulship).

[citation needed] The castrato sopranist Gioacchino Conti, known as Il Gizziello or heb ceilliau, was born in Arpino in 1714.

Near it is an ancient bridge, of a road which crossed the Liris to Cereatae (modern Casamari), birthplace of Gaius Marius.